Traditional medicine has a long history of disease prevention and control in public health. Today, a growing number of plants used in traditional medicine are being reported to exhibit a variety of activities in infectious disorders, notably viral infections, and thus could serve as additional antiviral sources. Due to its significant role in sustaining good health, traditional medicines are increasingly being used by various groups in many regions of the world, leading to rising awareness and research. According to the World Health Organization, the objective of "health for all" cannot be accomplished without the use of herbal medicines in basic care. To address increasing public health challenges, the centuries-old medical system is being re-examined. As a result, there is an urgent need to improve the drug development process for natural compounds, not just in the next 10 or 20 years, but also in the next 20-40 years and beyond.