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6th Edition of International Conference on

Traditional Medicine, Ethnomedicine and Natural Therapies

June 20-22, 2024 | Paris, France

Traditional Medicine 2024

Mei Hsien Lee

Speaker at Traditional Medicine, Ethnomedicine and Natural Therapies 2024 - Mei Hsien Lee
Taipei Medical University, Taiwan
Title : Unlocking healing potentials: Utilizing traditional chinese medicine formulation for alleviating osteoporosis symptoms


Population aging is a significant global concern, with osteoporosis emerging as a prevalent epidemic worldwide. Bone remodeling occurs within the body and involves the formation and growth of new bone tissue. In contrast, some existing bone tissue is absorbed and removed—a process regulated primarily by osteoblasts and osteoclasts. This study evaluates a randomized clinical trial (RCT) of traditional Chinese medicine formulation (TCMF) and the activity and mechanisms of TCMF using the zebrafish model. A 12- week randomized clinical trial (RCT) was conducted to assess the efficacy of TCMF in osteoporosis patients, employing various indices, including Bath Ankylosing Spondylitis indices, WHOQOL-BREF Taiwan, and Oswestry Disability Index. The RCT and gene pharmacology research results indicate that TCMF exhibits significant benefits, particularly in patients younger than 65 and those with a BMI <25. Furthermore, we conducted an activity and chemical molecular network strategy to explore the relationship between TCMF metabolites and in vivo activity. To investigate further, independent component analyses were conducted, aiming to identify key active ingredients for the future development of qualitative and quantitative analysis methods to establish quality control references.

Audience Take Away Notes:

  • Randomized clinical trial (RCT) of traditional Chinese medicine formulations (TCMF)
  • Chemical molecular network
  • In vivo zebrafish model


Prof. Lee holds BS, MS, and Ph.D. degrees from TMU School of Pharmacy. Her research, spanning Okayama University, Japan, and Academia Sinica, centers on analyzing biologically active constituents from Chinese medicines and Taiwanese endemic plants for medicinal products. Various models were used to identify active compounds targeting degenerative diseases, skin anti-photoaging, and osteoporosis. Rigorous chemistry, manufacturing, and control specifications ensure quality raw materials. The team, including traditional Chinese medicine doctors, conducts clinical trials, aiming to advance Chinese herbal medicine through interdisciplinary research, bridging from bench to bedside and vice versa.