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6th Edition of International Conference on

Traditional Medicine, Ethnomedicine and Natural Therapies

June 20-22, 2024 | Paris, France

Traditional Medicine 2024

Kosh Komba Ephrem

Speaker at Traditional Medicine, Ethnomedicine and Natural Therapies 2024 - Kosh Komba Ephrem
University of Bangui, Central African Republic
Title : Case study and phytochemical investigation of zanthoxylum zanthoxyloids and zanthoxylum macrophylum (Rutaceae) In the Central African Republic and Togo: A comparative approach


The study carried out on Z. zanthoxyloids and Z. macrophylum, lays on the program of valorizing phytogenetical resources. It covers monographic and phytochemical study. Inner uses of these resources show as well their importance on the scale of such African countries as Nigeria, Togo, Congo, Ivory Coast, Central African Republic, Benin, Senegal and Mali. Z. macrophylum is the most used species in the treatment of rheumatism. Over all the inner practices, Z. zanthoxyloids is the most used species. Analysis in multiple correspondences (AMC) with a partial contribution of 80% shows that there is a correlation of uses over all countries, except Senegal that has specific uses. Total extracts obtains from the two specific species from the Central African and Togolese flora have various yielding according to different organs. The most important proportions are that Z. macrophylum barks from Togo (20%); Z. zanthoxyloids barks from the Central African Republic (19%); Z. zanthoxyloids barks from Togo (17%) and Z. macrophylum barks and roots from the Central African Republic (16%). The issues of phytochemical tests showed the presence of alkaloids, of tannins, of flavonoids and saponosids in the organs of the two species. Meanwhile, one notices that : there is a total lack of alcaloids in the level of barks; the absence of saponisides in the level of Togolese and Central African Z. macrophylum leaves; tannins are also absent in the barks of Central African Z. zanthoxyloids barks and Togolese Zanthoxylum macrophylum roots. These differences in components according to Togolese and Central African Republic can be explained by chemotics which in a variety of in chemical components due to specific environmental factors of each milieu.


Professor Ephrem KOSH-KOMBA is a lecturer at the Faculty of Science of the University of Bangui and a lecturer at CAMES. He defended his thesis in January 2013 at the Faculty of Sciences of the University of Lomé, Togo, in collaboration with CIRAD-Montpellier, France. His research activities focus on natural substances, ethnobotany, agro-biodiversity and plant production. He is a member of the Laboratoire de Sciences Biologiques et Agronomiques at the Faculty of Science, University of Bangui, and is in charge of a regional project (RAF-5081) with the International Atomic Energy Agency.