AUM mantra is a basic core of the Indian Vedic Mantra, it is called the central sound of all kinds of sounds. AUM sound is basically made of three basic sounds Aaa…O and UM in Indian Vedic knowledge it is said that all other sounds can Be made by using these three basic sounds. Similar to the sound theory of universe; ancient Indian Vedic science also suggests the universe creation has been initiated by the big roar sound, created multiple times. In that case, the importance of sound in Indian Vedic Knowledge is very prominent and its effect on overall mental health has been reiterated many times in the Vedas and Upanishads of the Indian knowledge base. Consequential; Sound healing in Indian ancient time has been considered as very basic and very core kind of therapy, lots of specific mantras type of sounds and music has been created by using the intricacies of the ‘science of sound’ for the treatment of specific ailments of body and overall well-being of the human health. As sated AUM sound is a core of all complicated sound systems has been used for the wellness of mental health, this research would be made to re-establish the link between ancient Indian Vedic knowledge of sound on the mental health of humans in modern time. Scientifically the components of sounds are amplitude, resonance, wave form, pitch, tone etc. similar to this if a mantra (say AUM Chant) has been recited in controlled environment of lesser noise by using specific pitch, tone, and frequency and resonance can create and invoke an energy waveform that can change the chemistry and create new neural pathways to create better mental health, peace, wisdom and equanimity. Mental health can be measured by its components like enhancement of memory, better emotional intelligence, and better intelligence quotients, better decision making and agile functioning can be established with validated psychometric tests. The significance and purpose of such type of research would open new avenues of applying ancient knowledge in modern times and also will open the door for young researchers to usher for new and more subtle directions and dimensions in the health sector by blending ancient Indian Vedic knowledge with the modern ways.