Title : Determining the effectiveness of algal supplement on blood pressure: Systematic review and Meta-analysis of randomized controlled trials
Abstract:
The impact of Algae supplements and its extract on blood pressure has not concluded yet.In various studies included in the analysis, algae were administered in capsule form, ranging from 500 mg to 8 g. The duration of follow-up in these studies varied from 17 days to 9 months. The analysis utilized the standardized mean difference and its corresponding 95% confidence interval as the effect size to assess the impact of algae supplementation on systolic and diastolic blood pressure. The results of the meta-analysis will be presented, focusing on two groups of studies. Firstly, a meta-analysis of 10 studies with baseline effect control will be discussed. In this group, it was found that there was no significant difference in the mean systolic blood pressure between the treatment and control groups. The standardized mean difference (SMD) was -1.05, with a 95% confidence interval (CI) of -2.85 to 0.76. However, a significant difference was observed in the mean diastolic blood pressure, with the treatment group showing a lower mean diastolic blood pressure compared to the control group. The SMD for diastolic blood pressure was -2.23, with a 95% CI of -4.35 to -0.11. Additionally, a meta-analysis of 4 studies with no baseline control effect was discussed. In this group, no significant results were found for both systolic and diastolic blood pressure. It will be emphasized that while these findings provide some evidence regarding the antihypertensive activity of algae supplements, further investigation is needed. In conclusion, the presentation will provide an overview of the current status of research on the impact of algae supplements on blood pressure. The presentation highlight the importance of future large-scale randomized controlled trials (RCTs) to confirm these results. The findings suggest a potential effect on diastolic blood pressure, but more investigation is required.
Audience Take Away Notes:
- The impact of algae supplements and its extract on blood pressure is still inconclusive, indicating a need for further research and investigation.
- A systematic review meta-analysis was conducted to evaluate the antihypertensive activity of algae on humans, providing insights into the current state of knowledge in this area.
- The meta-analysis revealed that there was no significant difference in mean systolic blood pressure between the treatment and control groups when baseline effect control was considered. However, a significant difference was observed in mean diastolic blood pressure, with the treatment group showing lower values compared to the control group.
